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ALDX.US
id: 792

Aldeyra (ALDX) ADX-2191 Failed NDA Case

D. Massachusetts
Court
1:23-cv-11737
Case number
03/17/2022
Class period Start
06/20/2023
Class period End
09/29/2023
Lead Plaintiff motion deadline
  • FDA stated that there was a lack of effectiveness evidence in NDA for Aldeyra's ADX-2191.
  • $ALDX fell over 27%, losing $170 million of its market cap.
  • Investors suspect Aldeyra of failing to disclose that the ADX-2191 application did not include adequate investigations.
On June 21, 2023, Aldeyra (ALDX) announced receipt of a CRL from the FDA for the NDA of ADX-2191 (methotrexate for injection, USP), an investigational drug candidate, for the treatment of primary vitreoretinal lymphoma (PVRL). The press release stated that “although no safety or manufacturing issues with ADX-2191 were identified, the FDA stated that there was a lack of substantial evidence of effectiveness due to a lack of adequate and well-controlled investigations’ in the literature-based NDA submission.

On this news, $ALDX fell over 27%, losing more than $170 million of its market capitalization.

Taking all representations into account, Investors have reasons to suspect Aldeyra and its Accountables of misleading and failing to disclose that the ADX-2191 application did not include adequate and well-controlled investigations and thus failed to show substantial evidence of ADX-2191's effectiveness.
Case Status
Motion to dismiss
Alleged Offence
Misleading Statements
Failure to Disclose
Negligence
Omissions
Suspected Party
Directors
Management
Service Provider
Security Type
Stocks
Trade Direction
Long
Shock Event Date
06/21/2023
Filing date
07/31/2023
Lead Plaintiff Deadline
09/29/2023
Judge
Hon. Denise J. Casper
Collecting participants…

Aldeyra The

Aldeyra Therapeutics, Inc., a biotechnology company, develops and commercializes medicines for immune-mediated diseases. Its lead product candidate is reproxalap, a reactive aldehyde species (RASP)...

    Ticker
    ALDX.US
    ISIN
    US01438T1060
    CIK
    1341235
    Sector
    Healthcare
    Industry
    Biotechnology
    Country
    USA
    Address
    131 Hartwell Avenue, Lexington, MA, United States, 02421